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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPHOSPH6
All Species:
28.18
Human Site:
Y45
Identified Species:
51.67
UniProt:
Q99547
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99547
NP_005783
160
18996
Y45
I
I
S
E
E
H
W
Y
L
D
L
P
E
L
K
Chimpanzee
Pan troglodytes
XP_511131
160
18980
Y45
I
I
S
E
E
H
W
Y
L
D
L
P
E
L
K
Rhesus Macaque
Macaca mulatta
XP_001111939
160
19004
Y45
I
I
S
E
E
H
W
Y
L
D
L
P
E
L
K
Dog
Lupus familis
XP_536767
161
19124
Y45
I
I
S
E
E
H
W
Y
L
D
L
P
E
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1Q1
161
19067
Y45
M
I
S
D
E
H
W
Y
L
D
L
P
E
L
K
Rat
Rattus norvegicus
NP_001123353
161
19084
Y45
M
I
S
D
E
H
W
Y
L
D
L
P
E
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508366
152
17890
I52
L
K
E
K
E
S
F
I
I
E
E
Q
S
F
K
Chicken
Gallus gallus
XP_414172
261
29249
Y142
I
I
S
D
E
H
W
Y
L
D
L
P
D
L
K
Frog
Xenopus laevis
NP_001090153
164
19467
E52
L
D
L
P
E
L
K
E
K
E
S
Y
I
I
E
Zebra Danio
Brachydanio rerio
NP_001003618
168
19793
F45
I
I
S
D
E
H
W
F
L
D
L
P
E
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523609
162
18450
Q45
L
Y
S
N
E
I
N
Q
K
M
L
N
S
T
S
Honey Bee
Apis mellifera
XP_001122030
111
13233
M15
L
S
K
S
I
L
E
M
K
F
M
K
R
T
K
Nematode Worm
Caenorhab. elegans
O16207
189
21634
T53
T
E
K
E
A
E
A
T
C
S
T
E
I
L
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
98.7
91.3
N.A.
86.9
87.5
N.A.
73.7
48.2
68.9
62.5
N.A.
30.8
31.2
31.7
N.A.
Protein Similarity:
100
99.3
99.3
94.4
N.A.
93.7
95
N.A.
80
56.3
83.5
82.1
N.A.
52.4
49.3
49.2
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
13.3
86.6
6.6
86.6
N.A.
20
6.6
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
46.6
100
33.3
100
N.A.
26.6
20
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
8
0
31
0
0
0
0
0
62
0
0
8
0
0
% D
% Glu:
0
8
8
39
85
8
8
8
0
16
8
8
54
0
8
% E
% Phe:
0
0
0
0
0
0
8
8
0
8
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
62
0
0
0
0
0
0
0
0
0
% H
% Ile:
47
62
0
0
8
8
0
8
8
0
0
0
16
8
0
% I
% Lys:
0
8
16
8
0
0
8
0
24
0
0
8
0
0
85
% K
% Leu:
31
0
8
0
0
16
0
0
62
0
70
0
0
70
0
% L
% Met:
16
0
0
0
0
0
0
8
0
8
8
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
8
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
62
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
8
70
8
0
8
0
0
0
8
8
0
16
0
8
% S
% Thr:
8
0
0
0
0
0
0
8
0
0
8
0
0
16
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
62
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
54
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _